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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRTC3
All Species:
18.18
Human Site:
S375
Identified Species:
50
UniProt:
Q6UUV7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UUV7
NP_001036039.1
619
66959
S375
S
L
S
N
P
S
L
S
T
T
N
L
S
G
P
Chimpanzee
Pan troglodytes
XP_510592
618
66846
S375
S
L
S
N
P
S
L
S
T
T
N
L
S
G
P
Rhesus Macaque
Macaca mulatta
XP_001097976
618
66835
S375
S
L
S
N
P
S
L
S
T
T
N
L
S
G
P
Dog
Lupus familis
XP_545865
640
69541
P397
S
L
S
N
P
S
L
P
T
A
A
M
S
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91X84
619
67008
S375
S
L
S
N
P
S
L
S
T
T
N
L
S
G
P
Rat
Rattus norvegicus
Q3LRZ1
691
73127
S376
H
P
S
L
P
A
S
S
L
A
H
H
A
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233252
620
66878
V374
Q
Q
Q
Q
P
Q
V
V
S
S
L
P
Q
S
T
Frog
Xenopus laevis
Q52KS4
632
69330
S363
P
T
S
A
L
G
S
S
P
R
R
R
H
T
P
Zebra Danio
Brachydanio rerio
XP_698544
527
57276
S293
G
T
L
N
T
G
G
S
L
P
D
L
S
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.5
82.3
N.A.
88.8
40.8
N.A.
N.A.
38.5
49.3
39.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99
87.5
N.A.
93.6
54.2
N.A.
N.A.
53.5
62.8
52.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
100
26.6
N.A.
N.A.
6.6
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
46.6
N.A.
N.A.
26.6
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
0
0
0
23
12
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
23
12
0
0
0
0
0
0
56
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
12
12
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
56
12
12
12
0
56
0
23
0
12
56
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
67
0
0
0
0
0
0
45
0
0
12
0
% N
% Pro:
12
12
0
0
78
0
0
12
12
12
0
12
0
0
78
% P
% Gln:
12
12
12
12
0
12
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
12
12
0
0
0
% R
% Ser:
56
0
78
0
0
56
23
78
12
12
0
0
67
12
0
% S
% Thr:
0
23
0
0
12
0
0
0
56
45
0
0
0
12
12
% T
% Val:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _